Adiponectin is an adipocyte-derived hormone that exhibits insulin sensitizing properties, although the use of adiponectin as a therapeutic treatmentis infeasible due to its high circulating serum concentration, short half-life, complex molecular structure, and the discovery of adiponectin resistance. The beneficial effects of adiponectin are mediated by the adaptor protein APPL1, and its molecular signaling characteristics are of interest, as they are potential therapeutic targets.
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The University of Texas at San Antonio
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The University of Texas at San Antonio
The University of Texas at San Antonio